Cardiovascular Safety of Oral Antidiabetic Drugs.
نویسندگان
چکیده
منابع مشابه
Cardiovascular Safety of Oral Antidiabetic Drugs
SAŽETAK: Hrvatska pripada skupini europskih zemalja s visokim kardiovaskularnim rizikom i rastućom prevalencijom šećerne bolesti tipa 2 (DMT2). Prema podatcima Nacionalnog registra osoba sa šećernom bolešću (CroDiab registar), u Hrvatskoj je 2014. godine bilo evidentirano ukupno 254 296 osoba oboljelih od dijabetesa starijih od 18 godina (7,9 %). DMT2 je, uz hipertenziju i hiperlipidemiju, jeda...
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The prevalence of type 2 diabetes mellitus (T2DM) has increased rapidly over the past decade. In the Untied States, this increase has been greater than 40%. Obesity, which is closely linked to risk of developing T2DM, has likewise increased in prevalence by more than 60% during the same time period. Cardiovascular disease is the major cause of mortality among patients with T2DM, accounting for ...
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Oral antidiabetic drugs (OADs) are used for more than a half-century in the treatment of type 2 diabetes. Only in the last five years, intensive research has been conducted in the pharmacogenetics of these drugs based mainly on the retrospective register studies, but only a handful of associations detected in these studies were replicated. The gene variants in CYP2C9, ABCC8/KCNJ11, and TCF7L2 w...
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Diabetes mellitus (DM) is commonly diagnosed in cats. In humans, treatment regimens for non–insulin-dependent DM include various combinations of dietary modification, exercise, insulin administration, and one or more oral antidiabetic drugs, which have been extensively evaluated in humans but not in cats. Glucose toxicity is a phenomenon of chronic hyperglycemia and must be understood before in...
متن کاملMechanism of action of oral antidiabetic drugs.
The fall in blood sugar with carbutamide (BZ55) 24 hr. after the maintenance dose of insulin (28.1%+/-2.9 s.e) in rabbits made severely diabetic with alloxan was significantly different from the change in the blood sugar with the same drug given 72 hr. (6.8%+/-2.0) or distilled water given 24 hr. (7.7%+/-1.3) respectively after the last dose of insulin. It is postulated that the drug acts by li...
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ژورنال
عنوان ژورنال: Cardiologia Croatica
سال: 2016
ISSN: 1848-543X,1848-5448
DOI: 10.15836/ccar2016.285